Press has scored eight goals in the last eight matches. She had five goals in the recent CONCACAF Olympic qualifying tournament and was named the event’s MVP.
It was the 123rd career goal for Lloyd, who led the team in scoring last year with 16 goals.
Julie Ertz came close to scoring in the 78th minute but the United States was offside. Ertz was making her 100th appearance with the national team, becoming the 40th national team player to reach the milestone.
The game was a rematch of the World Cup semifinal last summer in France. The United States held on for the 2-1 win after Naeher smothered Steph Houghton’s penalty kick in the 84th minute.
Spain, ranked No. 13 in the world, plays the United States on Sunday when the tournament shifts to Red Bull Arena in New Jersey. No. 10 Japan will face sixth-ranked England in the other match.