At Nantes, Mbappe delivered an assist and scored from the spot, his seventh league goal this season.
The World Cup winner’s absence is a further blow to PSG, which will also be deprived of Neymar, Marco Verratti, Mauro Icardi and Julian Draxler against Leipzig.
PSG beat Leipzig in the Champions League semifinals last season before its 1-0 loss to Bayern Munich in the final.
The French champions are second on goal difference in Group H and ahead of third-place Leipzig after two matches. They lost their opening match at home against Manchester United and beat Istanbul Basaksehir 2-0 in Turkey last week.
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