Thompson, who is a sixth year senior, missed all but three games last year due to an injury to his throwing shoulder that required surgery. Thompson made his 32nd start at quarterback as a Wildcat, which tied him for most in school history.
“I was pretty emotional, I saw it happen last year and kind of had déjà vu,” Klieman said. “I’m devastated for him. We’ll pray for the best.”
Vaughn ran for 120 yards and three touchdowns while Malik Knowles had 112 receiving yards for Kansas State (2-0). Will Howard went 8-for-17 passing for 76 yards with a rushing touchdown and an interception.
Kansas State’s offense stalled absent Thompson. A 21-3 Wildcat lead in the first half turned into a 23-21 deficit by halftime. The Wildcats had three straight possessions with a turnover and finished with four total.
Nic Baker threw for 176 yards and Javon Williams Jr. ran for 46 yards and two touchdowns for Southern Illinois (1-1); a top 10 team in FCS. Baker threw for a Southern Illinois record 460 yards last week.
“I feel like they’re a good football team and we couldn’t get in a rhythm,” Southern Illinois coach Nick Hill said. “We had a chance in the end and we’ll all hold each other accountable for getting better.”
Southern Illinois: The Salukis saw an opportunity to exploit the Wildcats without Thompson and nearly pulled the upset.