From modeling airflows aboard medical evacuation aircraft to simulating vaccine candidates, the Defense Department’s supercomputing resources are being brought to bear on various aspects of the government’s pandemic response. Dr. Will McMahon and Dr. Kevin Newmeyer from the DoD High Performance Computing Modernization Program join Jared Serbu to share some examples. Later, we talk with Dr. Piyush Mehrotra, the chief of the Advanced Supercomputing Division at NASA about how his agency is contributing to the government’s supercomputing consortium for COVID-19.